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Peripheral Blood Products

Peripheral Blood Biospecimens are a critical tool in immunology research due to their significant role in protecting and maintaining healthy bodily functions. We use the term “Peripheral Blood” to describe a broad category of human biospecimens that are related to the human body’s circulatory system.

Peripheral blood is the primary method for transporting nutrients such as oxygen and carbon dioxide through the body and has 3 primary components: erythrocytes (red blood cells), leukocytes (white blood cells), and thrombocytes (blood platelets). The medium which allows these components to flow through the body is called blood plasma. Erythrocytes, or red blood cells, are the primary transportation mechanism for oxygen throughout the human body. In normal (healthy) samples, the mature form of the cell is non-nucleated, reddish, biconcave disk. Each of these cells contains hemoglobin, the iron-containing metalloprotein that allows for oxygen-transport. Leukocytes, or white blood cells, have a crucial role in the immune system and are meant to protect the body against diseases. In normal samples, they are a colorless blood corpuscle capable of ameboid movement. Blood platelets (thrombocytes) are the irregularly shaped disk-like particles in the blood and have no defined nucleus, DNA, or hemoglobin. Blood platelets contain active enzymes and mitochondria and are therefore primarily responsible for blood coagulation. Blood Plasma is the clear, yellowish fluid portion of blood, lymph, or intramuscular fluid in which these cellular components are suspended.

At Conversant Bio, we offer a wide variety of human peripheral blood samples from normal donors and from patients with cancer or autoimmune/inflammatory disorders. Some of the most popular peripheral blood products include our peripheral blood mononuclear cells, peripheral blood isolated B-Cells, and peripheral blood viable plated cells. To learn more about our individual peripheral blood products browse the items below. 

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Peripheral Blood Products

Peripheral Blood | Mononuclear Cellsdescribe the image

Mononuclear cells, mainly consisting of monocytes and lymphocytes, are obtained by gradient centrifugation using Ficoll. These cells are aliquoted and cryopreserved at -150C in a manner that maintains post-thaw cellular viability.

Key Applications:

  • drug testing and drug target discovery
  • assessing immune responses
  • toxicology studies
  • genetic studies
  • xenografting
  • cancer stem cells
  • cell isolation studies

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Peripheral Blood | Cell Isolations

describe the image

Isolated cells to match your research needs.  Examples of common requests for cell isolations include CD34+, CD138, CD3+, and CD19+.

Key Applications:

  • drug testing and drug target discovery
  • assessing immune response
  • toxicology
  • genetic studies

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Peripheral Blood | Circulating Tumor Cellsdescribe the image

Fresh peripheral blood (shipped the same day of draw for overnight delibvery) from patients with known circulating tumor cells as determined by Veradex. 

Key Applications:

  • biomarker identification/ validation
  • genetic studies
  • cell isolation
  • drug target discovery

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Peripheral Blood | Buffy Coatdescribe the image

Mononuclear cells, mainly consisting of monocytes and lymphocytes, are obtained by gradient centrifugation using Ficoll. These cells are aliquoted and frozen at -80C in a manner that maintains post-thaw cellular viability. 

Key Applications:

  • biomarker identification/ validation
  • genetic studies
  • drug target discovery

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Peripheral Blood | Plasmadescribe the image

Plasma is the liquid, non-cellular portion of blood. It contains a variety of proteins, nutrients, ions, hormones and clotting factors. 

Key Applications:

  • biomarker identification/ validation
  • genetic studies

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Peripheral Blood | Serumdescribe the image

Serum is the liquid, non-cellular portion of blood lacking clotting factors. It contains a variety of proteins, nutrients, ions, and hormones. 

Key Applications:

  • biomarker identification/ validation
  • genetic studies

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Peripheral Blood | Special Processingdescribe the image

Peripheral blood can be processed in a manner that best suits your research. Please provide us with a detailed description of how you will like the sample handled. To inquire about our special processing services please click the icon to the right and you will be directed to our contact page. There you will be able to fill out a form and describe the specific samples you are seeking. 

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