Bone Marrow

Bone Marrow is the birth place of the human immune system. A wide array of cell progenitors are found within the marrow and help researchers identify the causes of blood and autoimmune diseases.

Bone Marrow is the soft, flexible tissue found in the interior of bones. It is responsible for new blood cell production and is a critical component of the lymphatic system as a primary producer of lymphocytes. There are 2 types of bone marrow: red marrow, which consists mainly of hematopoietic tissue, and yellow marrow, consisting mainly of fat cells. The three primary components of blood (red blood cells, white blood cells, and platelets) are produced from red marrow. At birth, all bone marrow starts as red marrow but as the human body ages some of this red marrow turns into yellow marrow. Red marrow can be found in a variety of locations within human bones including the hip, breast, ribs, cranium, and vertebrae. Additionally, this marrow is found in the cancellous material at the epiphyseal ends of long bones (i.e, the femur and humerus). Yellow marrow is found in the medullary cavity – the hollow interior of long bones.

At Conversant Bio, we carry a variety of bone marrow samples obtained from both normal and diseased patients. The bone marrow cells can be purified to Bone Marrow Mononuclear Cells (BMMCs) or sold as a prospective fresh collection. To learn more about our current bone marrow inventory or inquire about your specific needs, please click on the links below. We are here to help you obtain the ideal biospecimens you need for your research. Because Patients Are Waiting…

Bone Marrow Products

Bone Marrow | Mononuclear Cells

Mononuclear cells, mainly consisting of monocytes and lymphocytes, are obtained by gradient centrifugation using Ficoll. These cells are aliquoted and cryopreserved at -150C in a manner that maintains post-thaw cellular viability.

Key Applications:

• drug testing and drug target discovery
• assessing immune responses
• toxicology studies
• genetic studies
• cancer stem cells
• cell isolation studies

Bone Marrow | Fresh Samples

Fresh bone marrow, shipped the same day of draw for overnight delivery, is available from various donors / patients. Because we obtain samples directly from patients and donors for overnight delivery please contact us to discuss your specific needs. We will work with you to obtain the exact specimens you need for your research.

Key Applications:

• drug testing and drug target discovery
• biomarker identification/validation
• assessing immune response
• toxicology
• genetic studies
• xenografting
• cancer stem cells
• cell isolation studies